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Surgical Neurology International
BASE DE DATOS A LA CUAL PERTENECE
PubMed Central, Scimago Journal Ranking, Scopus
TIPO DE MANUSCRITO
Carta al Editor
IDIOMA
Ingles
AUTORES DE LA SOCIEDAD
Carlos Cabrera-Cruzado
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Revista Médica de Trujillo
BASE DE DATOS A LA CUAL PERTENECE
LATINDEX, LILACS y REDIB
TIPO DE MANUSCRITO
Carta al Editor
IDIOMA
Español
AUTORES DE LA SOCIEDAD
Ángel Carlos Fabian-Alfaro, Estefani Brighite Galvez-Rodriguez
Introduction Aripiprazole is an atypical antipsychotic drug, and its use in the treatment of borderline personality disorder remains controversial. We aimed to determine the efficacy and safety of aripiprazole in patients diagnosed with borderline personality disorder. Methods The protocol was registered in PROSPERO (CRD42021256647) on July 2, 2021. PubMed, Scopus, Web of Science, Ovid-Medline, Embase, PsycINFO, and Cochrane (CENTRAL) were searched, without restriction by language or publication date. Furthermore, we searched ClinicalTrials.gov trial registries and the WHO International Clinical Trials Registry Platform. The inclusion criteria were randomized clinical trials including adult patients (> 18 years) diagnosed with borderline personality disorder according to the Diagnostic and Statistical Manual of Mental Disorders criteria. The quality of the included studies was determined using the Cochrane risk-of-bias for randomized trials (RoB-2) tool. Results We included two randomized clinical trials published in three articles. Among these, 76 patients were diagnosed with borderline personality disorder, with 38, 12, and 26 assigned to the aripiprazole, olanzapine, and placebo groups, respectively. The majority of patients were women (88.16%), with an age range of 22.1–28.14 years. Aripiprazole was shown to reduce psychiatric symptoms (obsessive–compulsive behavior, insecurity, depression, anxiety, aggressiveness/hostility, phobic anxiety, paranoid thinking, psychoticism, and somatization), anxiety, depression, anger, hostility, and clinical severity. The adverse effects included headache, insomnia, restlessness, tremor, and akathisia. In both studies, the risk of bias was high, which is somewhat concerning. Conclusions Aripiprazole has shown promising results in the treatment of patients with borderline personality disorder. More randomized clinical trials are required.
NOMBRE DE LA REVISTA
Research Square
BASE DE DATOS A LA CUAL PERTENECE
Scopus, Pubmed
TIPO DE MANUSCRITO
Revisión sistemática
IDIOMA
Inglés
AUTORES DE LA SOCIEDAD
Dennis Anthony Pino-Zavaleta, Susan K Campos-Rodriguez
Background: Intimate partner violence (IPV) against women is common during pregnancy and can have adverse mental health outcomes in women. Our objective was to evaluate the association between IPV and symptoms of depression in Peruvian pregnant women. Methods: In this study, we performed a secondary analysis of the Demographic and Family Health Survey, ENDES 2013–2019. The study population consisted of a subsample of married or cohabiting Peruvian pregnant women. IPV was defined as any reported violence (psychological, physical, or sexual) committed by the last partner of women. The symptoms of depression were measured using the Patient Health Questionnaire-9. Poisson regression-generalized linear models were used to calculate adjusted prevalence ratios (aPR) with their respective 95% confidence intervals (95% CI). Results: Overall IPV was 11.64%. The prevalence of psychological, physical, and sexual IPV was 6.92%, 8.56%, and 1.12%, respectively. After adjusting for confounding variables, IPV was associated with the symptoms of depression. Conclusion: One in 10 pregnant women experienced IPV, the most frequent type being physical violence. One in four pregnant women experiences depressive disorders. Furthermore, the presence of psychological, physical, or sexual violence independently doubles the probability of the occurrence of depression in Peruvian pregnant women.
NOMBRE DE LA REVISTA
Journal of Pharmaceutical Health Services Research
BASE DE DATOS A LA CUAL PERTENECE
Scopus
TIPO DE MANUSCRITO
Artículo original
IDIOMA
Inglés
AUTORES DE LA SOCIEDAD
Jerry K. Benites-Meza
Introduction: The current study aimed to quantitatively synthesize available evidence regarding the seroprevalence of human toxocariasis in Latin America and the Caribbean.
Methods: A systematic research involving six electronic databases was conducted using a research strategy that combined MeSH terms with free terms. Article selection and information extraction were performed using a double and independent approach. The Newcastle-Ottawa tool was used to assess the risk of bias in the included articles. The meta-analysis used the random-effects approach, with subgroup analysis and sensitivity analysis for risk of bias also being performed.
Results: We included 101 articles with a total of 31,123 participants. The studies were conducted between 1990 and 2022, with Brazil accounting for the largest number of studies (n = 37). The overall seroprevalence of human toxocariasis was 31.0% (95% CI: 27.0-35.0%, I2 = 99%). The prevalence of the main characteristics observed in seropositive patients were as follows: ocular toxocariasis (30.0%), asymptomatic (26.0%), and presence of dogs at home (68.0%). In addition, the seroprevalence was lower in studies including only adults than in those including children or both. In contrast, no differences in seroprevalences were found between studies conducted in the community and hospital.
Conclusion: The overall seroprevalence of human toxocariasis in Latin America and the Caribbean was high. Notably, our findings showed that the seroprevalence was increased among populations who kept a dog at home but was decreased in populations comprising only adults. Our findings can be used to establish epidemiological surveillance strategies for the prevention and early identification of toxocariasis.
NOMBRE DE LA REVISTA
Frontiers in Public Health
BASE DE DATOS A LA CUAL PERTENECE
PubMed Central, DOAJ, Google Scholar
TIPO DE MANUSCRITO
Revisión Sistemática y Metanálisis
IDIOMA
Inglés
AUTORES DE LA SOCIEDAD
Enrique A. Hernandez-Bustamante
Objectives To determine the association between self-medication with antibiotics (SMA) and purchase of brand-name drugs in Peru. Methods A secondary analysis was conducted using a nationally representative survey from 2014 to 2016. The exposure variable was self-medication (SM), which is defined as the purchase of drugs for self-administration without a medical prescription. The study outcome was the purchase of brand-name drugs (yes/no). Sociodemographic variables, such as health insurance and type of institution, were considered as confounders. To assess the association between SMA and the purchase of brand-name drugs, the crude prevalence ratios (cPR) and adjusted prevalence ratios (aPR) were calculated with their confidence intervals at 95% (95% CI) using a Poisson-type generalized linear model and considering the complex survey design. Key findings A total of 1862 participants were analysed; 54.4% of the participants were women with a mean age of 39.3 years. The prevalence rate of SMA was 54.3%, whereas that of the purchase of brand-name drugs was 55.3%. The adjusted Poisson regression analysis showed an association between SMA and the purchase of brand-name drugs (aPR = 1.28; 95% CI: 1.18–1.37).
NOMBRE DE LA REVISTA
Canadian Geriatrics Journal
BASE DE DATOS A LA CUAL PERTENECE
Scopus, Web of Science
TIPO DE MANUSCRITO
Artículo original
IDIOMA
Inglés
AUTORES DE LA SOCIEDAD
Jerry K. Benites-Meza
Objectives: To determine the association between self-medication with antibiotics (SMA) and purchase of brand-name drugs in Peru.
Methods: A secondary analysis was conducted using a nationally representative survey from 2014 to 2016. The exposure variable was self-medication (SM), which is defined as the purchase of drugs for self-administration without a medical prescription. The study outcome was the purchase of brand-name drugs (yes/no). Sociodemographic variables, such as health insurance and type of institution, were considered as confounders. To assess the association between SMA and the purchase of brand-name drugs, the crude prevalence ratios (cPR) and adjusted prevalence ratios (aPR) were calculated with their confidence intervals at 95% (95% CI) using a Poisson-type generalized linear model and considering the complex survey design.
Key findings: A total of 1862 participants were analysed; 54.4% of the participants were women with a mean age of 39.3 years. The prevalence rate of SMA was 54.3%, whereas that of the purchase of brand-name drugs was 55.3%. The adjusted Poisson regression analysis showed an association between SMA and the purchase of brand-name drugs (aPR = 1.28; 95% CI: 1.18–1.37; P < 0.001).
Conclusions: It was found that 5 of 10 respondents SMA. Approximately 6 of 10 respondents that SMA used brand-name drugs. SMA is associated with a higher probability of purchasing brand-name drugs.
NOMBRE DE LA REVISTA
Embase, ESCI, Scopus
BASE DE DATOS A LA CUAL PERTENECE
Pubmed, Scopus, Web of Science, EBSCO
TIPO DE MANUSCRITO
Análisis secundario
IDIOMA
Inglés
Background: Older adults are a particularly vulnerable group to drug use and self-medication. The aim of the study was to evaluate self-medication as a factor associated with the purchase of brand-name and over-the-counter (OTC) drugs in older adults in Peru.
Methods: A secondary analysis was performed using an analytical cross-sectional design of data from a nationally representative survey from 2014 to 2016. The exposure variable was self-medication, defined as the purchase of medicines without a prescription. The dependent variables were purchases of brand-name and OTC drugs, both as a dichotomous response (yes/no). Information of sociodemographic variables, health insurance, and the types of drugs purchased by the participants was collected. Crude prevalence ratios (PR) were calculated and adjusted using generalized linear models of the Poisson family, considering the complex sample of the survey.
Results: In this study, 1,115 respondents were evaluated, with a mean age of 63.8 years and a male proportion of 48.2%. The prevalence of self-medication was 66.6%, while the proportions of purchases of brand-name and OTC drugs were 62.4% and 23.6%, respectively. The adjusted Poisson regression analysis revealed an association between self-medication and the purchase of brand-name drugs (adjusted PR [aPR]=1.09; 95% confidence interval [CI]: 1.01–1.19). Likewise, self-medication was associated with the purchase of OTC medications (aPR=1.97; 95%CI: 1.55–2.51).
Conclusions: This study evidenced a high prevalence of self-medication in Peruvian older adults. Two-thirds of the surveyed people bought brand-name drugs, whereas one-quarter bought OTC drugs. Self-medication was associated with a greater likelihood of buying brand-name and OTC drugs.
NOMBRE DE LA REVISTA
Canadian Geriatrics Journal
BASE DE DATOS A LA CUAL PERTENECE
Pubmed, Scopus, Web of Science, EBSCO
TIPO DE MANUSCRITO
Análisis Secundario
IDIOMA
Inglés
ABSTRACT
The systemic immune-inflammation index (SIII) is a marker studied in multiple types of urologic cancer. This systematic review evaluates the association between SIII values with overall survival (OS) and progression-free survival (PFS) in testicular cancer. We searched observational studies in five databases. The quantitative synthesis was performed using a random-effects model. The risk of bias was assessed using the Newcastle–Ottawa Scale (NOS). The only measure of the effect was the hazard ratio (HR). A sensitivity analysis was performed according to the risk of bias in the studies. There were 833 participants in a total of 6 cohorts. We found that high SIII values were associated with worse OS (HR = 3.28; 95% CI 1.3–8.9; p < 0.001; I2 = 78) and PFS (HR = 3.9; 95% CI 2.53–6.02; p < 0.001; I2 = 0). No indication of small study effects was found in the association between SIII values and OS (p = 0.5301). High SIII values were associated with worse OS and PFS. However, further primary studies are suggested to enhance the effect of this marker in different outcomes of testicular cancer patients.
NOMBRE DE LA REVISTA
Diagnostics
BASE DE DATOS A LA CUAL PERTENECE
Pubmed, Web of Science, EBSCO, Scopus, Embase
TIPO DE MANUSCRITO
Revisión Sistemática y Metanálisis
IDIOMA
Inglés
