Prevalence of zoonotic and non-zoonotic Rickettsia in horses: A systematic review and meta-analysis

Prevalence of zoonotic and non-zoonotic Rickettsia in horses: A systematic review and meta-analysis

sábado, diciembre 17, 2022

ABSTRACT

In a broad sense, Rickettsiae are a group of microorganisms that can be transmitted mechanically or biologically to animals and humans. Rickettsioses are associated with hematic manifestations. Its prevalence in humans, dogs and other animals has been widely explored, but not in equine species.

To determine the prevalence of Rickettsia infection in horses.

A systematic review of the literature was carried out in five databases for the proportion of horses infected with Rickettsia, defined by molecular and immunological techniques. A meta-analysis was performed using a random-effects model to calculate the pooled prevalence and 95% confidence intervals (CI). The Cochran's Q test and the I2 statistic were used to assess the between-study-heterogeneity.

The pooled prevalence of Rickettsia in equines was 37.0% (95% CI: 26.0%-47.0%), with significant heterogeneity among studies (I2 = 98.12%). In the subgroup analysis, the prevalence of Rickettsia in horses was found to be 24.0% (95%CI: 10.0%-41.0%) for IFI, 47.0% (95%CI: 30.0%-64.0%) for IFA, 14.0% (95%CI: 11.0%-17.0%) for IFAT and 39.0% (95%CI: 0.0%-95.0%) for PCR.

There was a high prevalence of Rickettsia among horses, with some of the species being zoonotic, with their corresponding implications for humans, which increasingly are in close contact with equines, particularly horses and their ticks, posing a risk for spillover and transmission.

NOMBRE DE LA REVISTA

New Microbes and New Infections

BASE DE DATOS A LA CUAL PERTENECE

Pubmed, Scopus, Web of Science, EBSCO

TIPO DE MANUSCRITO

Revisión Sistemática y Metanálisis

IDIOMA

Inglés 

AUTORES DE LA SOCIEDAD 

Enrique A. Hernandez-Bustamante

LEER ARTÍCULO COMPLETO

Leer más...

Atherogenic index of plasma and coronary artery disease: A systematic review

Atherogenic index of plasma and coronary artery disease: A systematic review

martes, diciembre 06, 2022

Resumen

Various studies suggest that the atherogenic index of plasma (AIP) is associated with the risk of coronary artery disease (CAD) in different clinical scenarios. This review aimed to synthesize evidence of the association between AIP values and CAD. A literature search was carried out on four databases, namely, PubMed, Scopus, Web of Science, and Ovid-Medline. A handsearch was performed on preprint repositories (MedRxiv and Research Square). The effect measurements were expressed as odds ratios (OR) with their corresponding 95% confidence intervals (CI). For the quantitative synthesis, we employed a random-effects model. We analyzed 14 articles (with 40,902 participants) from seven different countries.

NOMBRE DE LA REVISTA

Open Medicine

BASE DE DATOS A LA CUAL PERTENECE

Scopus, Pubmed, Web of Science

TIPO DE MANUSCRITO

Revisión sistemática

IDIOMA

Inglés 

AUTORES DE LA SOCIEDAD 

Enrique A. Hernandez-Bustamante

LEER ARTÍCULO COMPLETO

Leer más...

Lymphocyte-to-Monocyte Ratio and Clinical Outcomes in Cholangiocarcinoma: A Systematic Review and Meta-Analysis

Lymphocyte-to-Monocyte Ratio and Clinical Outcomes in Cholangiocarcinoma: A Systematic Review and Meta-Analysis

martes, noviembre 01, 2022

Resumen

Lymphocyte-to-Monocyte ratio (LMR) has shown an association with survival outcomes in several oncological diseases. This study aimed to evaluate the association between LMR and clinical outcomes for cholangiocarcinoma patients. A systematic review and meta-analysis were performed to assess the association between LMR values and overall survival (OS), disease-free survival (DFS), recurrence-free survival (RFS) and time to recurrence (TTR) in cholangiocarcinoma patients. We used Hazard ratio (HR) and their 95% confidence interval (CI) as a measure of effect for the random effect model meta-analysis. The Newcastle–Ottawa Scale was used for quality assessment. The Egger test and funnel plot were developed for approaching publication bias. A total of 19 studies were included in this study (n = 3860). The meta-analysis showed that cholangiocarcinoma patients with low values of LMR were associated with worse OS (HR: 0.82; 95% CI: 0.71–0.96; I2 = 86%) and worse TTR (HR: 0.71; 95% CI: 0.58–0.86; I2 = 0%). DFS and RFS also were evaluated; however, they did not show statistically significant associations. Low LMR values were associated with a worse OS and TTR.

NOMBRE DE LA REVISTA

Diagnostics

BASE DE DATOS A LA CUAL PERTENECE

Scopus, Pubmed, Web of Science

TIPO DE MANUSCRITO

Revisión sistemática y meta-análisis

IDIOMA

Inglés 

AUTORES DE LA SOCIEDAD 

Enrique A. Hernandez-Bustamante

LEER ARTÍCULO COMPLETO

Leer más...

Acceptance towards Monkeypox Vaccination: A Systematic Review and Meta-Analysis

Acceptance towards Monkeypox Vaccination: A Systematic Review and Meta-Analysis

viernes, octubre 28, 2022

Resumen

Vaccination it is considered a vital strategy in order to mitigate monkeypox by protecting from severe disease and helping in reduction of hospitalisations. In this sense, this study aims to estimate the global prevalence of vaccination acceptance against monkeypox. We conducted a systematic review with a comprehensive search strategy for the following databases: PubMed, Scopus and Web of Science. A random-effect model meta-analysis was carried out using observational studies assessing the intention of vaccines against monkeypox from multiple continents. The quality assessment was developed using the Newcastle-Ottawa Scale adapted for cross-sectional studies. In addition, a subgroup analysis by study location and population and a sensitivity analysis was developed.Eleven cross-sectional studies were included. A total of 8045 participants were included. The pooled prevalence of monkeypox vaccination acceptance in all participants was 56.0% (95%CI: 42.0–70.0%). In the subgroup analysis of monkeypox vaccine acceptance according to continents, the prevalence of vaccine acceptance was 50.0% (95%CI: 24.0–76.0%) in Asian countries and 70.0% (95%CI: 55.0–84.0%) in European countries. The prevalence of vaccine acceptance was 43.0% (95%CI: 35.0–50.0%) in the general population, 63.0% (95%CI: 42.0–70.0%) in healthcare workers, and 84.0% (95%CI: 83.0–86.0%) in the LGBTI community. Despite the high prevalence of monkeypox vaccination acceptance in the LGBTI community found in our study, vaccination acceptance from healthcare workers and the general population are lower. Governments could use these results for planning, developing or promoting vaccination strategies and public health policies focused on these populations.

NOMBRE DE LA REVISTA

Pathogens

BASE DE DATOS A LA CUAL PERTENECE

Scopus, Web of Science, PubMed, PMC, Embase, PubAg, CaPlus/SciFinder, AGRIS

TIPO DE MANUSCRITO

Revisión sistemática y meta-análisis

IDIOMA

Inglés 

AUTORES DE LA SOCIEDAD 

Enrique A. Hernandez-Bustamante

LEER ARTÍCULO COMPLETO

Leer más...

Portal thrombosis in antiphospholipid syndrome: Case report

Portal thrombosis in antiphospholipid syndrome: Case report

domingo, octubre 16, 2022

Resumen

Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by arterial, venous, or small vessel thrombosis and recurrent early pregnancy loss, fetal loss, or pregnancy morbidity in the context of persistent antiphospholipid antibodies. Characterized by the development of multiple thrombotic manifestations, simultaneously or within a short period of time; being portal vein thrombosis (DVT) a rare and serious clinical manifestation and a predictor of poor prognosis.The case of an elderly patient with abdominal pain and portal vein thrombosis associated with APS with antithrombotic treatment and analgesics of favorable evolution is presented.

NOMBRE DE LA REVISTA

Revista de la Facultad de Medicina Humana

BASE DE DATOS A LA CUAL PERTENECE

Web of Science, Embase, Scielo, LILACS, DOAJ, Embase, CiteFactor, Latindex, Crossref, REDIB, ALICIA, Google Scholar, MIAR, DRJI, Dialnet, Harvard Library

TIPO DE MANUSCRITO

Reporte de caso

IDIOMA

Inglés 

AUTORES DE LA SOCIEDAD 

Elkin J. Pelaes Cruz

LEER ARTÍCULO COMPLETO

Leer más...

Propiedades beneficiosas del yacón (smallanthus sonchifolius) en la salud

Propiedades beneficiosas del yacón (smallanthus sonchifolius) en la salud

viernes, septiembre 30, 2022

Resumen

Introducción: El yacón (Smallanthus sonchifolius), es una planta nativa de las zonas andinas sudamericanas y se le han atribuido muchas propiedades beneficiosas para el organismo; entre las cuales destacan efectos antioxidantes, antimicrobianos, hipolipidémicos, antidiabéticos e incluso anticancerígenos. Objetivo: Ampliar el conocimiento sobre las propiedades funcionales atribuidas al yacón; para este propósito se hará una recopilación y lectura de los estudios publicados hasta la fecha sobre el yacón y se utilizarán para validar las propiedades beneficiosas que el yacón tiene sobre la salud. Materiales y métodos: Para el presente artículo se realizó una revisión sistemática desde noviembre del 2021 hasta enero del 2022, a través de búsquedas electrónicas en bases de datos como MedLine, PubMed y SciELO. Resultados: Este trabajo empieza con una breve descripción acerca de la fitoquímica del yacón; luego desarrolla las posibles propiedades antioxidante, antiinflamatoria, prebiótica, anticancerígena, hipoglicemiante e hipolipidémica atribuidas al yacón. Conclusiones: El yacón es un alimento muy nutritivo que cada vez se vuelve más conocido entre la población debido a la divulgación de sus propiedades beneficiosas, las cuales comprenden según la literatura consultada, efectos antioxidantes, antiinflamatorios, prebióticos, anticancerígenos, hipoglicemiantes e hipolipidémicos. Se considera necesario realizar más estudios sobre este alimento para dilucidar mejor sus efectos, ya que muchos de los datos reportados hasta ahora se originan en estudios con modelos animales y muy pocos con seres humanos.

NOMBRE DE LA REVISTA

Más Vita

BASE DE DATOS A LA CUAL PERTENECE

Latindex, LILACS, Google Scholar, Base, Road, World Cat, Research Bib, EuroPub, Scope Database

TIPO DE MANUSCRITO

Artículo original

IDIOMA

Español 

AUTORES DE LA SOCIEDAD 

Kevin Minchola-Castañeda

LEER ARTÍCULO COMPLETO

Leer más...

Red blood cell distribution width to predict mortality in heart transplant recipients: a systematic review

Red blood cell distribution width to predict mortality in heart transplant recipients: a systematic review

domingo, septiembre 04, 2022

Resumen

Red blood cell distribution width (RDW) has been shown to have prognostic value in a number of different clinical settings, such as cardiovascular disease, including heart failure. However, its prognostic value in heart transplant (HT) recipients remains unknown. The aim of this systematic review is to determine the prognostic value of pre-transplant RDW for mortality in HT recipients. There is a pre-published protocol of this review. The terms "Heart transplant", "Red cell distribution width" and their synonyms were used in the search strategy. PubMed/Medline, Embase, Scopus, Web of Science and LILACS were searched until May 17th, 2022, without date or language restrictions. Two authors independently carried out the selection, first by title and abstract, second by full-text revision. Discrepancies were discussed and resolved with three other authors. Quality of individual studies was assessed with Newcastle Ottawa Scale (NOS) for cohorts. After removing the duplicates, 3885 articles were identified. Four articles were included in the qualitative synthesis. Three studies were classified as "good quality": whereas one as "poor quality" according to NOS scale. All the included articles evaluated long-term mortality and one study also evaluated short-term mortality. In this one, a correlation between higher RDW values and short-term mortality was reported. Meanwhile, in all the studies, a high pre-HT RDW was a marker of long-term mortality following cardiac transplantation. Our review shows that an elevated on-admission RDW is associated with long-term mortality in heart transplantation recipients.

NOMBRE DE LA REVISTA

Monaldi Archives for Chest Disease

BASE DE DATOS A LA CUAL PERTENECE

Pubmed, Scopus

TIPO DE MANUSCRITO

Revisión sistemática

IDIOMA

Inglés 

AUTORES DE LA SOCIEDAD 

Luis Miguel Acuña Chávez

LEER ARTÍCULO COMPLETO

Leer más...

C-Reactive Protein-to-Albumin Ratio and Clinical Outcomes in COVID-19 Patients: A Systematic Review and Meta-Analysis

C-Reactive Protein-to-Albumin Ratio and Clinical Outcomes in COVID-19 Patients: A Systematic Review and Meta-Analysis

martes, agosto 16, 2022

Resumen

C-reactive protein-to-albumin ratio (CAR) is an independent risk factor in cardiovascular, cerebrovascular, and infectious diseases. Through this study, we investigated the CAR values with respect to the severity and mortality of COVID-19 patients. We performed a systematic review and meta-analysis to retrieve studies that evaluated CAR values upon hospital admission in relation to the severity or mortality of COVID-19 patients. We adopted a random-effect model to calculate the pooled mean difference (MD) and their 95% confidence intervals (CI). Quality assessment was appraised using a Newcastle–Ottawa scale and publication bias was assessed using the Begg-test and funnel plot. We equally performed a subgroup analysis using study location and a sensitivity analysis only with studies with low risk of bias. We analyzed 32 studies (n = 12445).

NOMBRE DE LA REVISTA

Tropical Medicine and Infectious Disease

BASE DE DATOS A LA CUAL PERTENECE

Scopus, Pubmed, Web of Science, Embase

TIPO DE MANUSCRITO

Revisión sistemática y meta-análisis

IDIOMA

Inglés 

AUTORES DE LA SOCIEDAD 

Enrique A. Hernandez-Bustamante

LEER ARTÍCULO COMPLETO

Leer más...

Association between Lipid Profile and Apolipoproteins with Risk of Diabetic Foot Ulcer: A Systematic Review and Meta-Analysis

Association between Lipid Profile and Apolipoproteins with Risk of Diabetic Foot Ulcer: A Systematic Review and Meta-Analysis

miércoles, agosto 10, 2022

Resumen

Background and Aims. Biomarkers are necessary to stratify the risk of diabetic foot ulcers (DFUs). This systematic review and meta-analysis aimed to evaluate the association between the lipid profile and apolipoproteins with the risk of DFU. Methods. A systematic search was conducted in PubMed, Scopus, Cochrane Library, and Web of Science among adult patients. Cohort and case-control studies were included. Random-effects models were used for meta-analyses, and the effects were expressed as odds ratio (OR) and their 95% confidence intervals (CIs). We evaluated publication bias through Egger’s test and funnel plot. Results. A total of 12 cohort studies and 26 case-control studies were included, with 17076 patients. We found that the higher values of total cholesterol (TC), low-density lipoprotein (LDL), triglycerides, and lipoprotein(a) (Lp(a)) were associated with a higher risk of developing DFU (OR: 1.47, OR: 1.47, OR: 1.5, OR: 1.85, respectively). Otherwise, the lower values of HDL were associated with a higher risk of developing DFU (OR: 0.49). Publication bias was not found for associations between TC, HDL, LDL, or TG and the risk of DFU. Conclusions. The high values of LDL, TC, TG, and Lp(a) and low values of HDL are associated with a higher risk of developing DFU. Furthermore, we did not find a significant association for VLDL, ApoA1, ApoB, and ApoB/ApoA1 ratio.

NOMBRE DE LA REVISTA

International Journal of Clinical Practice

BASE DE DATOS A LA CUAL PERTENECE

Scopus, Web of Science, Embase, Medline, Pubmed

TIPO DE MANUSCRITO

Revisión sistemática y meta-análisis

IDIOMA

Inglés 

AUTORES DE LA SOCIEDAD 

Enrique A Hernandez-Bustamante

LEER ARTÍCULO COMPLETO

Leer más...

Clinical features, hospitalisation and deaths associated with monkeypox: a systematic review and meta-analysis

Clinical features, hospitalisation and deaths associated with monkeypox: a systematic review and meta-analysis

martes, agosto 09, 2022

Resumen

Introduction A multicountry monkeypox disease (MPX) outbreak began in May 2022 in Europe, leading to the assessment as a potential Public Health Emergency of International Concern (PHEIC) on June 23, 2022. Some observational studies have partially characterised clinical features, hospitalisations, and deaths. However, no systematic reviews of this MPX outbreak have been published. Methods We performed a systematic review with meta-analysis, using five databases to assess clinical features, hospitalisations, complications and deaths of MPX confirmed or probable cases. Observational studies, case reports and case series, were included. We performed a random-effects model meta-analysis to calculate the pooled prevalence and 95% confidence interval (95% CI). In addition, we carried out a subgroup analysis according to the continents and a sensitivity analysis excluding studies classified as having a high risk of bias. Results A total of 19 articles were included, using only 12 articles in the quantitative synthesis (meta-analysis). For 1958 patients, rash (93%, 95% CI 80–100%), fever (72%, 95% CI 30–99%), pruritus (65%, 95% CI 47–81%), and lymphadenopathy (62%, 47–76%), were the most prevalent manifestations. Among the patients, 35% (95% CI 14–59%) were hospitalised. Some 4% (95% CI 1–9%) of hospitalised patients had fatal outcomes (case fatality rate, CFR). Conclusion MPX is spreading rapidly, with a third of hospitalised patients, but less than 5% with fatal outcomes. As this zoonotic virus spreads globally, countries must urgently prepare human resources, infrastructure and facilities to treat patients according to the emerging guidelines and the most reliable clinical information.

NOMBRE DE LA REVISTA

Annals of Clinical Microbiology and Antimicrobials

BASE DE DATOS A LA CUAL PERTENECE

Scopus, CABI, CAS, Citebase, DOAJ, Embase, Global Health, Medline, Pubmed, Scimago, Zetoc

TIPO DE MANUSCRITO

Revisión sistemática y meta-análisis

IDIOMA

Inglés 

AUTORES DE LA SOCIEDAD 

Enrique A. Hernandez-Bustamante

LEER ARTÍCULO COMPLETO

Leer más...

Prevalence of parents' non-intention to vaccinate their children and adolescents against COVID-19: A comparative analysis in Colombia and Peru

Prevalence of parents' non-intention to vaccinate their children and adolescents against COVID-19: A comparative analysis in Colombia and Peru

miércoles, julio 27, 2022

 

ABSTRACT

We aimed to estimate the prevalence and factors associated with parents’ non-intention to vaccinate their children and adolescents against COVID-19 in Colombia and Peru. We performed a secondary analysis using a database generated by the University of Maryland and Facebook (Facebook, Inc). We Included adult (18 and over) Facebook users residing in LAC who responded to the survey between May 20, and November 5, 2021. We Included sociodemographic characteristics, comorbidities, mental health, economic and food insecurity, compliance with mitigation strategies against COVID-19, and practices related to vaccination against this disease. We estimated crude (cPR) and adjusted (aPR) prevalence ratios with their respective 95 %CI. We analyzed a sample of 44,678 adults from Colombia and 24,302 from Peru. The prevalence of parents' non-intention to vaccinate their children and adolescents against COVID-19 was 7.41 % (n = 3,274) for Colombia and 6.64 % (n = 1,464) for Peru. In Colombia, age above 35 years old, compliance with physical distancing, use of masks, having economic insecurity, anxiety symptoms, having a chronic condition or more comorbidities, and being vaccinated were associated with a higher probability of vaccinating children and adolescents against COVID-19. In Peru, female gender, compliance with physical distancing, use of masks, having economic insecurity, anxiety symptoms, having a chronic condition or more comorbidities, having had COVID-19, and being vaccinated were associated with a higher probability of vaccinating children against COVID-19. Living in a town, a village, or a rural area was associated with a higher prevalence of non-intention to vaccinate children and adolescents against COVID-19. About 9 out of 10 parents in Colombia and Peru intend to vaccinate their children and adolescents against COVID-19. This intention is associated with some factors which are similar between the two countries, as well as other factors and variations among the different regions of each country.

NOMBRE DE LA REVISTA

Vaccine: X

BASE DE DATOS A LA CUAL PERTENECE

Embase, Scopus, DOA, Web of Science, PubMed Central

TIPO DE MANUSCRITO

Análisis Secundario

IDIOMA

English 

AUTORES DE LA SOCIEDAD 

Jerry K. Benites Meza

LEER ARTÍCULO COMPLETO

Leer más...